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1998年水灾后6个受灾省病毒性肝炎的病原学调查

Investigation on Etiology of Viral Hepahtis in Six Flood Stricken Provinces of China in 1998

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【作者】 曹惠霖; 戴淑玲; 贾志远; 李建东; 黄玉英; 朱荣; 王建军; 周小凤; 殷文武; 李守邦; 董杰; 詹美云;

【Author】 CAO Hui-lin, DAl Shu-Iing, JlA Zhi -Vuan, et al. Institute of Virology, Chinese Academy ofPreventive Medicine, BeUing 100052, China.

【机构】 中国预防医学科学院病毒学研究所!北京市; 100052; 中国预防医学科学院疾病控制处; 江苏省卫生防疫站; 安徽省卫生防疫站; 江西省卫生防疫站; 黑龙江省;

【摘要】 为了解1998年水灾后病毒性肝炎的主要流行型别,于1999年2~4月,在6个受灾省(自治区,下同)收集了就诊肝炎病人血清1135份.用酶联免疫吸附试验检测甲、乙、戊型肝炎感染指标.结果表明:(1)在水灾后的病毒性肝炎病例中,约半数为急性肝炎(45.73%),半数可能为慢性乙型肝炎(54.27%),后者少数为其它型肝炎;(2)在急性肝炎中,甲、乙、戊型肝炎分别占57.42%、30.06%和12.52%;(3)在HBsAg阳性者中,能定为急性肝炎的只占32.21%.在这里21%的急性肝炎中甲、乙、戊型肝炎的比例分别为26.18%、68.06%和5.76%,表明水灾区的急性病毒性肝炎以甲型肝炎为主,慢性肝炎以乙型肝炎为主.上述两种类型是水灾后预防的重点。

【Abstract】 In order to investigate the major epidendc types of viral hepatitis after theflood strike in 1998 in China, we collected 1 135 serum samples of hepatitis patients fromhospitals of 6 flood stricken provinces (the autonomous region, the same below) in Februa-ry ~April 1999, and tested the samples for hepatitis infectious markers, IgM of HAV, HBcand HEV by ELISA. The results showed that ① Half of the hepatitis cases after floodstrike were acute hepatitis (45.75%), the other half were mostly chronic hepatitis B with afew of other types of hepatitis, ② Of the acute hepatitis, hepatitis A, B and E accountedfor 57.42%, 30.06% and 12.52% respectively, ③ In HBsAg positive hepatitis cases, 32.21 %of them could be determined as acute hepatitis, among them the lgM positivity of hepatitisA, B and E were 26. 18%, 68.08% and 5.76% respectively. It demonstrated that in the floodstricken provinces in 1998, the acute viral hepatitis was chiefly of hepatitis A and the chron-ic viral hepatitis was the hepatitis B. These two types of hepatitis may be considered as theimportant preventive objects after flood strike.

【关键词】 病毒性肝炎; 病原学分型; 抗-HAVIgM;
【Key words】 Viral hepatitis; Typing of agents; Anti-HAV IgM;
  • 【文献出处】 中国计划免疫 ,CHINESE JOURNAL OF VACCINES AND IMMUNIZATION , 编辑部邮箱 ,1999年05期
  • 【分类号】R181.3
  • 【下载频次】13
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