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乙型糖尿病(Ⅱ型DM)危险因素及遗传度研究
Study on Risk Factor and Heritability of NIDDM
【摘要】 对哈尔滨市7家大医院住院病人,采用1∶1配比病例对照研究,使用条件Logistic模型进行分析。单因素分析结果提示:身高、体重、脑力劳动、病毒感染和遗传5个因素为Ⅱ型DM的危险因素。多因素分析表明:体重超重、病毒感染及遗传为Ⅱ型DM的危险因素,体育锻炼为保护性因素。遗传研究表明:Ⅱ型DM属多基因遗传,遗传度为58.74%。
【Abstract】 We have analyzed the risk factor and heritability of NIDDM by 1∶1 matched case control study in the seven hospitals in the harbin.The result of univariate analysis showed that height,weight,mental labour,infection and heriditary are the risk factors of NIDDM.The result of multivariate analysis showed that weight、infection and heriditary are the risk factors of NIDDM.On the contrary,the exercise is preventive factor.In addition.the rersult of heriditary study is that NIDDM belongs to multigene heriditary,heritability of NIDDM is 58 78%.
【关键词】 糖尿病;
病例对照研究;
危险因素;
遗传度;
【Key words】 Diabetes\ Matched case control study\ Risk factors\ Herilability;
【Key words】 Diabetes\ Matched case control study\ Risk factors\ Herilability;
- 【文献出处】 中国公共卫生 ,CHINA PUBLIC HEALTH , 编辑部邮箱 ,1999年04期
- 【被引频次】3
- 【下载频次】77