【摘要】 目的:分析抗感染药物引起的不良反应。方法:收集《中国药学文摘》(1994年～1998年9月)报道的有关抗感染药物不良反应病例,并按倒数排序进行分析。结果:排列前三位的药物为青霉素类、喹诺酮类、头孢菌素类;其中严重不良反应535例,主要为过敏性休克和肝、肾功能损害。结论:临床应加强对抗感染药物的合理应用,避免和减少不良反应的发生。更多还原

【Abstract】 Objective: To analyse the adverse drug reactions induced by antiinfective drugs. Methods: Reported cases of adverse drug reactions related to antiinfective drugs were collected from Chinese Pharmaceutical Abstracts (1994~September, 1998), and arranged in order according to the number of cases for analysing. Results: Penicillins, quinolones and cephalosporins were in the first three places; and serious adverse drug reactions amounted to 535 cases, chief among the reactions were allergic shocks and functional damage to liver and kidney. Conclusion: Rational use of antiinfective drugs should be strengthened in the clinical practice in order to prevent and reduce the occurence of adverse drug reactions.更多还原