【摘要】 用大肝大脾 （ Ｂ Ｌ Ｓ） 因子人工接种３ 月龄美国王鸽后进行病理学动态研究。结果表明， 其组织病理学特征主要侵害肝、脾和肾脏， 表现为肝、脾变性、坏死及大量淋巴细胞、浆细胞和巨噬细胞呈弥漫性或结节状增生， 膜性肾小球肾炎， 此外 Ｂ Ｌ Ｓ 因子还严重损害胸腺和法氏囊， 表现为淋巴细胞数目减少或耗尽。通过组织病理学研究和琼扩试验的结果， 证实了用鸡的 Ｂ Ｌ Ｓ 因子人工接种美国王鸽已获得成功。 Ｂ Ｌ Ｓ 因子不仅可以感染鸡， 也可感染美国王鸽。更多还原

【Abstract】 Big liver and spleen disease(BLSD)was produced experimentally by oral inoculation of BLS agent to 3 month American king pigeons.The results showed that the pathological effects were characterized mainly by injured liver,spleen and kidney,including degeneration and necrosis with diffuse and nodular proliferation of lymphocytes,plasma cells and macrophages,and membranous glomerulonephritis.Thymus and bursa of Fabricius were also injured with decrease or exhaust of lymphocytes,which demonstrated that BLSD was directly related to immune.The studies of histopathology and agar gel precipitin test(AGPT)demonstrated that BLS agent from chicken could be successfully inoculated orally into white Pigeons,which suggested that BLS agent infected not only broiler breeders,but also American king pigeons.更多还原