【摘要】 目的采用扫描电镜对大肠癌的表面微细变化进行观察。方法对肿瘤不同部位及肿瘤边缘5cm的粘膜标本进行常规电镜制备处理c结果癌细胞表面有两种类型：一种具有不典型微绒毛，一种没有微绒毛，呈颗粒状。在距肿瘤边缘5cm处，即可见到结肠粘膜上皮细胞表面微绒毛出现不典型的倾向。结论以上变化说明癌肿的扩展增大有可能是由于癌周边组织增生，逐渐移行转变为癌组织，本研究为大肠癌手术治疗和理论研究提供参考。更多还原

【Abstract】 Objective To observe the superficial tiny variations in carcinoma of large intestine under scanning electron microscope. Methods specimen of different parts of carcinoma and the mucosa at 5 cm from cancer border were prepared by routine procdure, and observed under scanning electron microscope manifesting. Results There are two types of changes on the surface of cancer cells, one atypical microvilli , and the other presenting granules without microvilli There appear also atypical microvilli on epithelial surface of laarge intestinal mucosat in the pariphery 5 cm from the cancer border. Conclusion The above mentioned variations suggest that the cancerous diffusion probably orginates from hyperplasia of surrounding tissues, which gradually fransform into carcinomatous tissues.This result is of signifiance for surgical treatment and basic study of carcinome of large intestine.更多还原