【摘要】 目的　研究不稳定性心绞痛（ＵＡＰ）、急性心肌梗死（ＡＭＩ）病人血清铁蛋白（ＳＦ） 的变化。方法　将住院治疗的４９ 例冠状动脉粥样硬化性心脏病（ＣＨＤ） 患者分为稳定性心绞痛（ＳＡＰ）、ＵＡＰ、ＡＭＩ组。其中ＳＡＰ９ 例，ＵＡＰ２７ 例，ＡＭＩ１３ 例，对照组３０ 例。ＡＰ和ＡＭＩ发作２４ 小时内的抽取空腹静脉血，分离血清，－ ４５ ℃保存，利用双抗体１２５Ｉ放射免疫法测定ＳＦ。结果　ＡＭＩ组ＳＦ 与对照组比较，ＡＭＩ组ＳＦ 增高，差异呈高度显著性（ Ｐ ＜０－０１）。结论　ＳＦ增高可能是ＣＨＤ的一个危险因素。ＳＦ在ＡＭＩ时增高与心肌损伤有关，用络合剂减少ＳＦ释放的Ｆｅ３＋ 有可能减轻心肌损伤更多还原

【Abstract】 Objective To study the changes of serum ferritin in unstable angina pectoris and acute myocardial infarction.Methods 49 cases of hospitalized CHD patients were divided into 3 groups.9 of them were in the SAP group,27 in the UAP group and 13 in the AMI group.30 cases were in control group.Before meal,the vein blood of the CHD patient group and the control group was drawn within 24 hours after the attack.The sera were centrifugalized and then preserved in a -45℃ ice box for measurement.The quantity of SF was measured with double-antibody\+\{125\}I radio-immunoassay.Results The SF of the AMI group was increased(P<0\^01).Conclusion The increaseof SF may be a risk factor of CHD and may relate to myocardial damage of AMI,and so it may be a method of taking a complex compound to decrease the quantity of Fe\+\{3+\} from SF to reduce the myocardial damage of AMI.更多还原