【摘要】 目的观察引导组织再生术诱导发育性骨裂隙骨再生融合的作用，为引导组织再生术在唇腭裂骨性裂隙修复中的应用提供实验依据。方法将国产聚四氟乙烯膜盖于兔下颌骨正中缝唇舌两侧，通过放射和病理检查，观察骨缝融合的情况。结果引导组织再生术能在4周左右诱导骨裂隙完全骨融合。结论引导组织再生术是修复骨性裂隙的有效方法，有可能用于齿槽裂、跨裂的骨性修复。更多还原

【Abstract】 Objective To observe the effect of guided tissue regeneration (GTR ) on induction of ostegenesis in developmental bone clefts,and provide a basis for the use of GTR to repair bony clefts in cleft lip and palate patients. Methods The e-PTFE membrane was placed on the labial and lingual sides of the rabbit mandibular central fissure. A radiological and pathological study was performed to determine the healing of the fissure integration. Results The results showed that the bony cleft was completely integrated 4 weeks after placement of the barrier membrane-.Conclusions GTR is an effective approach to reconstruct bony cleft ,and is likely to be used in repair of alveolar cleft and cleft palate.更多还原