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一阶导数紫外分光光度法测定茶碱的血药浓度
Determination of Theophylline in Human Serum by First Order Derivative UV-Spectrophotometry Method
【摘要】 采用一阶导数紫外分光光度法进行茶碱血药浓度测定,此法灵敏度高,专一性强,线性良好(r=0.9999,回收率较高,变异性小(RSD<5%)。用于临床茶碱血药浓度监测,方法简便准确,并收到满意效果。
【Abstract】 The theophylline concentration by a first order derivative UV-spectrophotometry in human serum was determined. The method had advantage of higher sensitivity, stronger specificity, and better linearity (r=0.999 9). The rate of recovery was higher (total CV<5%), the variability was less. This is a better examining method for clinical theophylline serum concentration monitoring, and being simple and presise.
【关键词】 导数光谱;
茶碱;
血药浓度;
【Key words】 First order derivative spectrophotometry; Theophylline; Monitoring of serum drug concentration;
【Key words】 First order derivative spectrophotometry; Theophylline; Monitoring of serum drug concentration;
- 【文献出处】 中国药师 ,China Pharmacist , 编辑部邮箱 ,1998年02期
- 【分类号】R96
- 【被引频次】2
- 【下载频次】82