节点文献
0.1%利凡诺溶液稳定性考察
Study on Stability of 0.1 % Rivanoli Solution
【摘要】 目的:考察0.1%利凡诺溶液和加入0.01%硫代硫酸钠的0.1%利凡诺溶液的稳定性。方法:采用紫外分光光度法测定含量,通过初均速法测定室温贮存期。结果:0.1%利凡诺溶液和加入0.01%硫代硫酸钠的0.1%利凡诺溶液,室温下(20℃)贮存期分别为154天和611天。20℃,1000LX光照下,反应速度常数K分别为3.7467×10-4mg/ml/h和2.4897×10-4mg/ml/h。结论:后者稳定性高于前者。
【Abstract】 Objective To test the stability of 0. 1 % rivanoli solution and 0. 1 % rivanoli solution containing0. 01 % sodium thiosulfatis. Methods: The rivanoli content were determined by UV spectrophotometry,and thestability test was conducted by the initial average rate method. Results: The shelflife of 0. 1 % rivanoli sulution atroom temperature was 154 days while that of 0. 1 % rivanoli solution containing 0. 01 % sodium thiosulfatis was611 days. Under light of 1000 Lx at room temperature .the reaction rate constant of 0. 1 % rivanoli solution was3. 7467 × 10-4mg/ml/h, while that of 0. 1 % rivanoli solution containing 0. 01 % sodium thiosulfatis was 2. 4897× 10-4mg/ml/h. Conclusion:The latter was more stable than the former.
【Key words】 Rivanol solution; Thiosulfates; Drug stability; Ultraviolet spectrophotometry;
- 【文献出处】 浙江医科大学学报 , 编辑部邮箱 ,1998年02期
- 【分类号】R96
- 【下载频次】53