节点文献

肾上腺素能受体在脾脏红细胞储存与释放的动力机制中的作用

THE EFFECT OF ADRENERGIC RECEPTORS ON THE DYNAMIC MECHANISM OF SPLENIC RESERVE AND DISCHARGE RED BLOOD CELLS

  • 推荐 CAJ下载
  • PDF下载
  • 不支持迅雷等下载工具,请取消加速工具后下载。

【作者】 孙树津龙天渝俞为群蔡绍皙

【Author】 Sun Shujin,Long Tianyu,Yu Weigun,Cai Shaoxi (Bioengineering Institute of Chong Qing University, The Open Laboratory on Biomechanic and Biorheology under the Slate Education Commission Chong Qing China 630044)

【机构】 重庆大学生物工程研究院国家教委生物力学及生物流变学开放实验室!重庆630044重庆大学生物工程研究院国家教委生物力学?

【摘要】 通过对狗的脾脏进行a受体阻断情况下的低浓度肾上腺素溶液在体 灌注实验,探讨了脾脏储存与释放血细胞的微循环动力机制.实验结果支持Groom 提出的脾索内肌质纤维在交感神经控制下的血液调节机制,并认为脾索及静脉窦 壁的过滤作用是调节脾内红细胞浓度的主要因素,但并非如 Mackenzie和 J rgen 等人认为的红细胞被动地滞留于脾索中,而是存在交感神经及血液中儿茶酚胺调 控下的主动机制。

【Abstract】 The splenic red blood cell reserve and discharge mechanism was studied by perfusing adrenaline solution of low concentration into splenic arteries after a-receptors in the spleen were blocked in anaesthetized dogs. The analysis to the experiments supports the splenic blood regulation mechanism involving active contraction of intra-reticulocytic skeletal filamets under the control of sympathetic nerve proposed by Groom. Red blood cells are not reserved passively by filtration of the red pulp as Mackenzie and Jorgen suggested, but by active dilation of reticulocytes or endotheliocytes of venous sinuses controlled sympathetic nerve and catechnolamine in blood.

  • 【文献出处】 中国血液流变学杂志 ,Chinese Journal of Hemorheology , 编辑部邮箱 ,1998年01期
  • 【分类号】R318.01
  • 【被引频次】33
  • 【下载频次】36
节点文献中: