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缺血性脑卒中患者早期复发的临床特征和危险因素

Early Recurrent Ischemic Stroke-A CaseControl Study

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【作者】 董瑞国庄柏翔谭迎春花放樊红彬沈霞

【Author】 Dong Ruiguo,Zhuang Beixiang,Tan Yingchun,et al. Department of Neurology, The First Teaching Hospital of Xuzhou Medical College,Jiangsu, 221002

【机构】 徐州医学院第一附属医院神经科

【摘要】 为探讨缺血性脑卒中患者早期复发的临床特点和危险因素,对复发的缺血性卒中患者进行了临床分析和病例-对照研究。结果637例完全性缺血性卒中,有24例复发,其总复发率为3.8%(24/637),其中脑血栓的复发率为3.4%(20/591),脑栓塞为8.7%(4/46)。大部分病例(71%,17/24)复发发生在原患侧,且多为同卒中类型复发(83%,20/24)。经McNemar卡方检验发现高血压史、有TIA或脑梗塞史、糖尿病等因素与对照相比有显著性差异,而缺血性心脏病、房颤、入院时高血糖、血脂增高和吸烟与复发无显著相关。认为缺血性脑卒中患者早期复发多为同卒中类型、同部位的复发,高血压、有TIA或脑梗塞史、糖尿病可能为卒中早期复发的危险因素。

【Abstract】 We carried out a casecontrol (1∶1 matched) study to identify the clinical characters and risk factors of early recurrent ischemic stroke. The results as follows: of 637 patients of cerebral infarction,24 cases with recurrent stroke and the total recurrent rate was 3.8%(24/637), of which, the recurrent rate of cerebral thrombosis was 3.4%(20/591) and that of cerebral embolism was 8.7%(4/46).71%(17/24) early recurrent stroke occurred in the same lateral side of previous stroke and 83%(20/24) were of the same stroke subtype.By McNemar χ2 test,we found the risk factors of history of hypertension,diabetes mellitus and TIAs or prior stroke were associated with early recurrence, however,factors such as ischemic cardiac disease, atrial fibrillation,hyperglycemia,hyperlipidemia and cigarette smoking were not associated with it. 

【关键词】 卒中复发病例-对照研究
【Key words】 Stroke Recurrent Case-control study
  • 【文献出处】 临床神经病学杂志 ,JOURNAL OF CLINICAL NEUROLOGY , 编辑部邮箱 ,1998年02期
  • 【分类号】R743.3
  • 【被引频次】25
  • 【下载频次】148
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