【摘要】 目的研究大肠癌肿瘤组织中巨噬细胞的浸润与大肠癌生物学特性的关系。方法用抗巨噬细胞抗体经ＳＰ免疫组织化学方法对８３例不同分期的大肠癌及其正常粘膜组织进行巨噬细胞浸润检测。结果大肠癌肿瘤组织中浸润的巨噬细胞明显较正常组织中为多；巨噬细胞浸润与大肠癌的转移、分期、分化及预后有关。巨噬细胞浸润多者，其转移发生率低，分期较早，分化也较好，且患者术后的生存率也较高。结论巨噬细胞的浸润与大肠癌的生物学特性有关，参与大肠癌的免疫反应过程更多还原

【Abstract】 Objective\ To study the relationship between the infilitration of macrophages in colorectal carcinoma and the biological character of colorectal carcinoma.\ Methods\ Infiltration of macrophage was determined by immunohischemistry use antimacrophage body in 83 different stage colorectal carcinomas.\ Results\ The number of macrophage’s infiltration in colorectal carcinomas are more than its normal mucosae.\ The infiltration of macrophage is associated with the metastatic status,Dukes stage,differentiation and prognosis.\ Conclusion\ The infiltration of macrophages in colorectal are associated with its biological charactor,they join the course of the tumor immune.更多还原