【摘要】 目的：旨在探索临床应用同位素标记方法检测神经再生的可能性。方法：采用改良氯胺Ｔ法制备１２５Ｉ－酪氨酸，用微量注射器直接注射入大鼠坐骨神经干内。术后不同时间取样，以γ－计数器检测其放射性。结果：发现１２５Ｉ－酪氨酸可以被坐骨神经直接吸收并转运，吸收时间约２小时，转运速率约１ｍｍ／ｈ。结论：该结果为体内直接检测轴浆流转运提供了实验依据更多还原

【Abstract】 Objective: To test the possibility of evaluating nerve regeneration by detecting the radioiodined axoplasm in vivo. Methods: Tyrosine was labeled with 125 I by using modified chloramine T method. 125 I Tyrosine was then injected directly into the sciatic nerve trunk by a microsyringe. The radioactivity of each sample was detected in a γ counter in different interval. Results: Animal experiments showed that 125 I Tyrosine could be absorbed and transported in rat’s sciatic nerve. The absorption time was about 2 hours. The transportation speed was about 1mm/h. Conclusion: Detection of axoplasm transportation in vivo by radioiodined tyrosine is practicable.更多还原