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福建省1994~1996年急性弛缓性麻痹病例病毒分离情况分析

VIRUS ISLATION FROM ACUTE FLACCID PARALYSIS(AFP) CASES IN FUJIAN PROVINCE FROM 1994 TO 1996

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【作者】 潘伟毅何亚玲杨秀惠郑金凤

【Author】 Pan Weiyi He Yaling Yang Xuhui Zheng Jinfeng (Fujian Provincial Epidemic Prevention Station,Fuzhou,350001)

【机构】 福建省卫生防疫站

【摘要】 对福建省1994~1996年急性弛缓性麻痹(AFP)监测系统送检的257例粪便标本进行病毒分离,共检出脊髓灰质炎(脊灰)病毒(PV)21株,其中4株为I型野毒株。3年PV分离阳性率分别为19.6%、4.9%、6.4%;分离到非脊灰肠道病毒(NPEV)24株,阳性率分别为0、5.9%、16.5%。结果表明,福建省PV季节高峰已消除,野病毒已连续2年未分离到,而NPEV分离率逐年在提高。AFP病例的病原型别也从以往的I型野病毒为主转为以NPEV和疫苗株为主。其中Ⅱ型疫苗株检出率明显上升。此外,还揭示了福建省5岁以下婴幼儿PV携带率最高,NPEV感染仍以夏秋季为主。

【Abstract】 We detected two hundred and fifty seven stool specimens of AFP cases that came from AFP surveillance system in Fujian Province from 1994 to 1996.Of the enteroviruses isolated,21 were poliovirus strains in which four were wild type-1 poliovirus strains,the positive isolation rate by year was 19.6%,4.9% and 6.4% respectively, 24 were non-polio enterovirus strains,the positive isolation rates were 0,5.9% and 16.5% respectively in these three years.The resultsindicated that the seasonal distribution features of poliovirus had disappeared and no wild poliovirus was detected during the last two years.The isolation rate of non-polio enterivirus rose in 1995 and 1996 in Fujian.The data also indicated that the dominant virus type was not wild-type 1,but the non-polio enteroviruses and vaccine strains of AFP cases in Fujian at present,among them we can find that the isolation rate of type 2 vaccines train rose obviously.In additon,it also revealed that the non-polio enteroviruses were still superior in summer and autumn and the childrenunder five years old had a higher poliovirus carrier rate.

  • 【文献出处】 中国计划免疫 ,CHINESE JOURNAL OF VACCINES AND IMMUNIZATION , 编辑部邮箱 ,1997年04期
  • 【分类号】R373.22
  • 【被引频次】2
  • 【下载频次】23
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