节点文献

免疫沉淀法用于A群流脑多糖菌苗的鉴别试验

Immuno precipitation Method Used in Identity Test for Meningococcal Polysaccharide Vaccine Group A

  • 推荐 CAJ下载
  • PDF下载
  • 不支持迅雷等下载工具,请取消加速工具后下载。

【作者】 边淑娟孙淑滨张静程夷

【Author】 Bian Shujuan,Sun Shubin,Zhang Jing,et al (Lanzhou Institute of Biological Products,Lanzhou,730046)

【机构】 卫生部兰州生物制品研究所

【摘要】 本文将免疫沉淀法——免疫双扩散及对流免疫电泳法用于A群流脑多糖菌苗的鉴别试验。并对其检测A群流脑多糖菌苗的特异性及敏感性与传统采用的间接血凝抑制试验法进行了比较。试验结果表明,免疫沉淀法准确、特异性好、操作简便、经济。完全符合WHO规程及中国规程中对《A群脑膜炎球菌多糖菌苗制造及检定规程》鉴别试验的要求。因此可望替代现行的间接血凝抑制试验,以作为今后A群流脑多糖菌苗鉴别试验的常规测定法

【Abstract】 Using immuno precipitation method (immuno double diffusion and counter immuno eletrophoresis) as the identity test for meningococcal polysaccharide vaccine group A.The specificity and sensityvity were studied and compared with traditional indirect hemagglutination inhibition test(HIT).The results show that new methods are accurate,specificity,easily operating and economical.They fulfill WHO and China Requirements of manufacture and control of meningococcal polysaccharide vaccine group A.Therefor,the new methods are respected to replace the HIT as the identity test methods of meningococcal polysaccharide vaccine group A.

  • 【文献出处】 微生物学免疫学进展 ,PROGRESS IN MICROBIOLOGY AND IMMUNOLOGY , 编辑部邮箱 ,1997年01期
  • 【分类号】R392-33
  • 【下载频次】82
节点文献中: