【摘要】 循经诱导“手阳明大肠经”（电针刺激“曲池”、“臂”穴）后，采用免疫细胞化学染色法，观察对同经线上“禾”穴和“人中”交会穴以及对非同经线上的“承浆”穴区内P物质（SP）和神经肽Y（NPY）免疫反应阳性神经的影响。结果发现在“人中”穴、“禾”穴区，电针刺激可使分布于皮下浅层的细小血管旁、皮脂腺、毛囊旁周以及皮下组织内的游离神经末梢的SP免疫反应性明显减弱，甚至消失。其SP免疫阳性纤维数量（密度）也明显减少（P＜0．01）。而电针刺激使肌层内的小血管壁周旁的NPY免疫反应性明显增强，NPY免疫阳性纤维数量（密度）也明显增多（P＜0．01）。但对“承浆”穴区内的SP和NPY免疫反应活性和阳性纤维数量（密度）均无明显的影响（P＞0．05）。提示循经电针诱导可激发同经线上的SP大量释放，抑制NPY释放，这种激发和抑制作用具有明显的循经特征，进一步说明SP和NPY可能是经脉线上传递信息的重要化学物质。更多还原

【Abstract】 After giving electroacupuncture (EA) stimulation at "Quchin" and "Binao" on the Hand-Yangming Large Intestine Channel with immunocytochemical techniques, we observed the changes of sub-stance P (SP)-and neuropeptide Y (NPY )-immunoreactive (IR ) nerves at "Heliaoh and "Renzhong" acupoints on the same meridian as well as "Chengjiang" acupoint on a different meridian. It was found that after EA,the intensity of SP-IR nerve fibers around small blood vessels, sebaceous glands and fair follicles as well as free nerve endings in hypodermis at "Renzhong" and "Heliao" was obviously weakened, even disappeared,the density of SP-IR fibers also decreased significantly compared to those in non-EA group(P<0.01),while both the intensity and the density of NPY-IR nerve fibers along the small blood vessels in the muscular layer increased remarkably. But no distinct change of SP-or NPY-IR was found at "Chengjiang"acupoint. These re-sults suggest that the influence of EA on SP-and NPY-IR possesses a character of meridian transmission,while SP and NPY may act as the chemical components for signal transmission along the meridian.更多还原