【摘要】 通过测量齿状核T1弛豫时间，设计出齿状核功能成象破坏稳态梯度回波序列的成象参数，并用此序列在一正常志愿者，在静止和刺激时交替扫描3次，进行齿状核功能成象，刺激时齿状核信号平均强度是静止时的1．2倍．静止和刺激时齿状核信号强度没有重叠更多还原

【Abstract】 Based on the measurements of T1 relaxation time of cerebellar dentate nuclei, we determined thebest parameters of a gradient echo MRI sequence for functional imaging of cerebellar dentate nuclei.With the sequence we performed functional MRI of cerebellar dentatc nuclei in a normal volunteer.The average increase of signal intensity was 20 % during activation state compared with that in restingstate. And there was no overlap in signal intensity between resting state and during hand toy matchingtask.更多还原