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三种肿瘤标志物对常见肿瘤诊断和预后的应用
Apply the Three Tumor Markers to Diagnosis and Evalute the Curative Effect of Common Carcinoma
【摘要】 目的:观察血清癌胚抗原(CEA)、血清铁蛋白(SF)和乳酸脱氢酶(LDH)联检对恶性瘤诊断和预后的作用。方法:106例恶性肿瘤患者血清 CEA、SF 用酶联免疫吸附法(ELISA)检测,血清 LDH 同工酶用聚丙烯酰胺凝胶电泳法分析。结果:食管癌、肺癌和乳腺癌的阳性率分别达82%,91%和93%。结论:此三种指标联检可明显提高癌肿的诊断率和评价疗效。
【Abstract】 Objective:The aim of these assay was to observe the effect of carcino-embrynic antigen (CEA),serum ferritin(SF)and lactic dehydrogenase(LDH)on the diagnosis and prognosis of carcino- ma.Methods:The serum levels of CEA and SF were assayed with enzyme linked immunosorbent assay (ELISA),and the isoenzyme pattern of LDH in the serum was studied with polyacrylamide gel elec- trephoresis in 163 patients with carcinoma.Results:The positive rates were 82%,91% and 93% respec- tively in esophagus carcinoma lung cancer and breast cancer.Conclusion:The results demostrate that posi- tive rates of carcinoma were greatly increased when the three targets were assayed at the same time and the markers are valuable in comment response to the therapy.
【Key words】 carcino-embryonic antigen; ferritin; lactic dehydrogenase; esophagus carcinoma; lung cancer; breast cancer;
- 【文献出处】 河南医学研究 ,Henan Medical Research , 编辑部邮箱 ,1997年01期
- 【分类号】R730.4
- 【被引频次】2
- 【下载频次】52