【摘要】 应用彩色多普勒超声心动图技术，以随机双盲的方法对比卡托普利（Ｃｐ）和硝苯吡啶（Ｎｄ）治疗６０例高血压病Ⅱ期病人６个月前后的ＬＡ、ＬＶＤｄ、ＬＶＳＴ、ＰＷＴ、ＬＶＭＩ、Ｅ、Ａ，结果两组病人血压均显著下降。ＣＰ组ＬＶＷＩ下降的百分数２８．１２±７．２％，显著高于Ｎｄ组的１３．４３±８．２％（Ｐ＜０．０１）。提示逆转ＬＶＨ，Ｃｐ优于Ｎｄ。Ｃｐ、Ｎｄ两组治疗前后Ｅ升高和Ａ下降的百分数无显著差异，提示Ｃｐ和Ｎｄ均能改善ＬＶＤＦ，但两者之间无差异。更多还原

【Abstract】 Sixty patients with mild to moderate essential hypertension were randomly assigned to either captorpril(Cp group n=30)or Nifedipine(Nd group n=30)treatment in a double blind control six months(M6).M mode 2 D and pulsed Doppler echocardiograms were performed at baseline and the end of trail.The change of the LV mass index(LVMI)and E、A were calculated. At M6 the Bp levels had a significant reduction both two groups(p<0 01).In Cp group LVMI from 152±32 to 125±34 g/m 2(p<0 01) In Nd group LVMI from 148±29 to 131±26 g/m 2(p<0 05) The percent of E increased and A reduced.That showed no significant change in both groups.更多还原