【摘要】 采用反转录-PCR（RT-PCR）技术，成功地从人胎肝细胞mRNA中获得了血小板生成素（TPO）信号肽和成熟肽编码区cDNA。序列分析表明，该cDNA序列与DeSauveg等报道的人TPO相应的核苷酸序列完全一致，为TPO基因工程的进一步研究打下基础。更多还原

【Abstract】 Human thrombopoietin cDNA including signal and mature peptide has been successfully obtained by means of reverse transcription polymerase chain reaction (RT- PCR) from fetal livermRNA. Sequence analysis indicated that the sequence of human TPO cDNA was the same as that ofhuman TPO cDNA reported by De Sauvage et al. It laid foundation for further study of genetic engineering.更多还原