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小鼠胸腺基质细胞系(MTEC1)在裸鼠体内生物学特性研究

Study on the effects of mouse thymic epithelial cell line MTEC 1 after intrasplenic injection of nude mice

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【作者】 张平夏张国荣肖士云刘祝公陈慰峰

【Author】 Zhang Pingxia,zhang Guorong , xiao shiyun, et al. (Department of Immunology , Beijing Medical University, Beijing 100083)

【机构】 北京医科大学免疫系!100083

【摘要】 通过流式细胞仪(FACS)、组织学染色和免疫组化的方法研究了脾内注射的小鼠胸腺上皮细胞系MTEC1和初代培养的小鼠胸腺基质细胞在裸鼠脾脏内存活状态及功能特性。结果发现MTEC1细胞不仅能够在脾脏内存活,而且在MTEC1细胞周围有大量不成熟的淋巴细胞。初代培养的小鼠胸腺基质细胞则不能在脾脏内存活。

【Abstract】 Study on the effects of mouse thymic epithelial cell line MTEC 1 after intrasplenic injection of nude mice was carried out with cytometry HE stain immunochemistry and PFC analysis. The results showed that the MTEC 1 cells not only can survive in the spleen but also there were a great deal of immature lymphocytes around MTEC1 cells. In contast ,the primarily cultured stromal cells of mouse thymus injected into the spleen nude mice could not survive any more .

  • 【文献出处】 中华微生物学和免疫学杂志 ,Chinese Journal of Microbiology and Immunology , 编辑部邮箱 ,1996年03期
  • 【分类号】R341
  • 【被引频次】4
  • 【下载频次】38
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