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快速酶联免疫吸附法检测血清脂阿拉伯甘露糖-IgG对肺结核的诊断价值

Detection of lipoarabinomannan-IgG in serum for the diagnosis of pulmonary tuberculosis

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【作者】 马玙高薇薇赵丰增古淑香黄学锐

【Author】 Ma Yu, Gao Weiwei, Zhao Fengzeng, et al. Beijing Tuberculosis and Thoracic Tumor Institute, 101149

【机构】 北京市结核病胸部肿瘤研究所卫生部结核病控制项目办公室北京市结核病胸部肿瘤研究所 101149101149

【摘要】 目的评估脂阿拉伯甘露糖-IgG(LAM-IgG)检测对活动性肺结核的诊断价值。方法采用快速酶联免疫吸附法(ELISA)检测90例肺结核、53例肺癌患者及30例正常人血清中的LAM-IgG。结果肺结核组LAM-IgG阳性率为82%,其中痰结核杆菌涂(+)培(+)组达96%,涂(—)培(—)组为69%:肺癌组4例阳性,正常组1例阳性。假阳性率分别为8%和3%。结论提示血清LAM-IgG测定是肺结核患者一项有用的辅助诊断手段。

【Abstract】 Objective To ascertain the value of lipoarabinomannan-lgG (LAM-IgG) determination in the diagnosis of pulmonary tuberculosis. Medthod LAM-IgG in sera obtained from 90 patients with acitve pulmonary tuberculosis, 53 patients with lung cancer and 30 healthy individuals were detected by using rapid enzyme-linked immunosorbent assay (ELISA). Results The positive rate was 82% in tuberculosis group, and the false positive rates were 8% and 3% in cancer group and healthy controls respectively. Conclusion The results suggested that rapid ELISA for LAM-IgG detection was a useful supplementary tool for diagnosis of pulmonary tuberculosis.

  • 【文献出处】 中华结核和呼吸杂志 ,Chinese Journal of Tuberculosis and Respiratory Diseases , 编辑部邮箱 ,1996年01期
  • 【分类号】R521
  • 【被引频次】65
  • 【下载频次】70
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