【摘要】 为探索食管癌超分割放疗适宜的剂量，１９８７年３～９月我们对８０例中段食管鳞癌患者随机分为３组进行对照研究：Ａ组总量为６０～７０Ｇｙ／６～７周，每天１次２Ｇｙ，每周５次；Ｂ组总量为５１Ｇｙ／２３天，每天２次，每；１．５Ｇｙ；Ｃ组总量为５０Ｇｙ／２３天，每天３次，每次１Ｇｙ。所有病人随诊超过５年，５年生存率Ａ、Ｂ、ＣＭ组分别为１１．１％、３７％和２３．１％。Ｂ组与Ａ组比较Ｐ＜０．０５。结果表明，总量为５１Ｇｙ的每天２次超分割放疗，具有疗程短、经济负担轻、生存率高等优点，治疗食管癌是可行的。更多还原

【Abstract】 From march 1987 to September 1987,80 patients with esophageal carcinoma were randomized into three groups.In group A the patients were treated with irradiation which was scheduled 2G/day,5 sessions/week with a total dose of 60-70 Gy in 6-7 weeks.In group B the irradiation was given by 1. 5uy/session,2sessions/day 10 sessions/week with a total dose of 51Gy in 23 days;and in group.C the irradiation was given by 1Gy/Session,three sessions/day,15 sessions/week with a total dose of 50Gy in 23 days.All patients were followed for more than 5 years.The 5-year survival rates in group A,B and C were 11. 1%,37% and 23. 1%respectively.There is significant difference between goup B and A(P<0.05).Owing to the advantages of shorter treatment course,less cost and higher survival rate,the authors believe that the hyperfractionated irradiation at a schedule of twice a day merits further observation.更多还原