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急性脑梗塞患者红细胞免疫功能与血清SOD、LPO的变化

Red blood cell immune adherence with the dynimic changes of free radical metabolism in the acute cerebral infarct patients

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【作者】 阎伟许二赫张昀

【Author】 Yan Wei;Xu Erhe;Zhang Yun.(Department of Neurology, Second Teaching Hospital, Bethune Norman University of Medical Sciences, Changchun 130041)

【机构】 白求恩医大二院神经内科

【摘要】 测定了31例急性脑梗塞患者红细胞C3b受体花环率(RBC—C3bRR)和红细胞免疫复合物花环率(RBC—ICR)以及可能影响红细胞免疫粘附(RCIA)功能的血清脂质过氧化物(LPO)、超氧化物歧化酶(SOD)。结果表明,急性脑梗塞患者RBC—C3bRR明显降低,而RBC—ICR明显增高;血清SOD含量减少,LPO明显增高。RBC—C3bRR降低与血清LPO增高呈显著负相关,与SOD呈正相关。上述结果说明红细胞免疫功能降低与体内自由基代谢改变有关。

【Abstract】 This paper detected the dynimic changes of the following four indexes in 31 cases with acute cerebral infarction. These indexes includes the red blood cell. C3breceptor rate(RBC-C3b RR), the red blood cell immune complex rate(RBC-ICR), serum lipid peroxide(LPO) which might affect the function of red blood cell immune adherence(RCIA). and superoxide dismutase(SOD). Results showed that the RBC-C3bRR was significantly lower,but RC-ICR higher in the acute cerebral infarct patients, simultaneously their serum SOD content decreased but that of LPO increased significantly. There were negative correlation between the decreasing of RBC-c3bRR with the increasing of serum LPO, correlation with SOD, Above results suggest that the decreasing of RBC immune reaction may relate with the changes of internal free radical metabolism.

【关键词】 脑梗塞红细胞免疫SODLPO
【Key words】 Cerebral infarction Red blood cell immune SOD LPO
  • 【文献出处】 中风与神经疾病杂志 ,JOURNAL OF APOPLEXY AND NERVOUS DISEASES , 编辑部邮箱 ,1996年04期
  • 【分类号】R743.330.3
  • 【被引频次】9
  • 【下载频次】33
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