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聚合酶链反应检测久治不愈的性病病原体

Detection of Pathogens of sexually transmitted disease hanging on for a long time by polymerase chain reaction.

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【作者】 刘晓莉; 白中华; 王立新; 扬慕莹; 李学萍;

【Author】 Liu Xiaoli,Bai Zhonghua,Wang Lixin,et al.(Department of Dermatology,The Second Affiliated Hospilal of Kunming Medical College 650101)

【机构】 昆明医学院第二附属医院检验科;

【摘要】 用聚合酶链反应(PCR)检测108例病程在2月以上的久治不愈的性病患者的病原体,结果淋球菌DNA阳性44例(40.7%)、沙眼衣原体DNA阳性36例(33.3%)、解脲支原体DNA阳性30例(27.8%),部分病例同时作淋球菌培养。沙眼衣原体免疫荧光检测及解脲支原体培养检出阳性率均低于PCR法。淋球菌和支原体检测二法阳性率有非常显著性查异(P<0.001),衣原体检测二法阳性率无显著性差异(P>0.05)。本次检测使76.9%的患者明确了病因学诊断,进行了针对性治疗,治愈率达86.6~92.3%。PCR检测在久治不愈的性病患者中有临床应用价值。

【Abstract】 Using polymeras chain reaction(PCR)to detect the pathogens of 108 patients with sexually transmitted disease over two months duration,the result showed that 44 of them were neieseria gonorrhoeae DNA positive(40.7%),36 were chlamydia trachornatis DNA positive(27.8%).Through PCR detection,the diagnosis of 76.9% patients was confirmed,and the curing rate was up to 86.6-92.3%.

  • 【文献出处】 云南医药 ,MEDICINE AND PHARMACY OF YUNNAN , 编辑部邮箱 ,1996年05期
  • 【分类号】R446.5
  • 【下载频次】10
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