【摘要】 报告5例脊索瘤（包括2例软骨脊索瘤）,3例位于骶尾部,2例分别在蝶鞍区和盆腔腹膜后.年龄17～52岁.免疫染色显示:5例Keratin弥漫阳性,4例Cytokeratin、EMA和Vimentin均阳性,5例S—100和α₁—ACT灶性阳性。2例软骨脊索瘤的软骨区也示Keratin、Cytokeratin或EMA灶性阳性。上述结果表明,Keratin、Cytokeratin和EMA等抗体在脊索瘤尤其软骨脊索瘤的鉴别诊断中很有实用价值。更多还原

【Abstract】 5 chordomas (including 2 chondroid chordomas)were reported . Among them 3 cases were at the sacrococcygeal region,1 at the spheno-occipital region,another 1 at the retroperitoneal region of the pelvic cavity. Age ranged from 17 to 52 years. Immunostain result showde that 5 cases were positive for keratin,S-100 and α1-ACT. 4 cases were positive for cytokeratin. EMA and vimentin. In the chondroid chordomas, cell within both the cartilaginous and conventronal areas stained for keratin. Cytokeratin or EMA. The present study confirms the utility of cytokeratin. Keratin and EMA in the differential diagnasis of chordoma (especially chondroid chordoma)and tumors with similar histologic charactrtistics.更多还原