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应用巯甲丙脯酸运动肾显像评价原发性高血压患者的肾功能

RENAL FUNCTIONAL EVALUATION OF PA-TIENTS WITH ESSENTIAL HYPERTENSlON USINGCAPTOPRIL-EXERCISE RENAL SCINTIGRAPHY

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【作者】 杨红张承刚刘建中韩钢韩秀琴李清

【Author】 Yang Hong; Zhang Chenggang; Liu Jianzhong ,et al. (Dept. of Nuclear Medicine, First MffiliatedHospital of Shanxi Medical College. Taiyuan 030001)

【机构】 山西医学院第一附属医院核医学科

【摘要】 用巯甲丙脯酸运动肾显像(Cap-Ex-RS)观察29例正常人及56例原发性高血压(EH)的肾功能。结果显示BUN及Scr正常的EH患者其基础肾显像(BSL)的全肾平均通过时间(KMTT)及高峰时间(TP)比正常人明显延长(P<0.01),不变(N)及缩短(S)组的介入KMTT比正常人明显缩短(P<0.05),延长(P)、N、S三组间差异显著。表明Cap-Ex-RS是一灵敏的评价EH早期肾功能改变的方法,可对EH进行分组并指导治疗。该法简单、灵敏、准确、重复性好,是集总肾及分肾功能与形态为一体的功能、影像诊断方法。

【Abstract】 he renal function was evaluated in 29 normalsubjects and 56 patients with essential hypertension(EH) in Captopril-exercise renal scintigraphy (Cap-Ex-RS). The results showed that the whole kidneymean transit time (KMTT) and the time of peak (TP)of BSL in patients with EH whose BUN and Scr werenormal were significantly prolonged and the KMTT ofintervention in N and S groups was significantly re-duced than that of the normal subjects. There weresignificant differences among 3 EH groups. Our datademonstrated that the Cap-Ex-RS was a sensitivemethod for detecting the early impairment of renalfunction in patients with EH. This method can also beused for classification of EH and guiding treatment ofEH. It is not only a simpie and reliable method for de-tecting split renal function but an image of both kid-neys and urinary tracts.

  • 【文献出处】 中华肾脏病杂志 ,CHINESE JOURNAL OF NEPHROLOGY , 编辑部邮箱 ,1995年05期
  • 【分类号】R544.1
  • 【被引频次】2
  • 【下载频次】26
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