【摘要】 本文对23例新生儿窒息及呼吸衰竭患儿采用高效液相色谱-电化学检测法测定去甲肾上腺素（NE）和肾上腺素（E），10例正常脐血为对照组，结果显示，窒息及呼衰缺氧可导致交感神经系统活性增强，分泌NE与E明显增多，急性期87．51±35．31pg／ml与恢复期38．55±21．77pg／ml比较差异非常显著（P＜0．01），与脐血56．35±26．82pg／ml比较，P＜0．05。随呼衰加重NE与E水平均增高，Ⅰ型61．44±33．48与Ⅱ型100．4±22．31（P＜0．05）。NE与PO2呈负相关，r＝－0．414，但无统计学差异。更多还原

【Abstract】 Plasma catecholamine (noradrenaline and adrenaline) was determined in the neonatal asphyxia and respiratory failure of 23 cases by high performance liquid chromatography with electro chemical detecti9n (HPLC-ECD), Umbilical blood of 10 cases was controlled. The results showed: 1. Hypoxia of asphyxia and respiratory failure caused increase of sympathetic nervous system activity to secrets NE and E. Compared the value of acute stage (87. 51±35. 31pg/ml) with convalesent stage (38. 55±21. 77). between which there was considerable statistical difference (P<0. 01). 2. NE and E levels increased was aggravation of hypoxia.Value of Ⅰ type of RF was 61. 44±33. 44,Ⅱ type was 100. 4±22. 31 (P<0. 05). 3. NE and PO2 showed negative correlation (r= -0. 414) but there was on statistical difference.更多还原