【摘要】 用一种新的红细胞保存添加剂ＧＭＡ（Ｇｌｕｃｏｓｅ，Ｍａｎｎｉｔｏｌ，Ａｄｅｎｉｎｅ）和目前欧美国家已常规使用的红细胞保存添加剂ＳＡＧＭ（Ｓａｌｉｎｅ，Ａｄｅｎｉｒｅ，Ｇｌｕｃｏｓｅ，Ｍａｎｎｉｔｏｌ）分别重悬ＡＣＤ浓缩红细胞制成ＳＡＧＭ红细胞悬液（ＳＡＧＭ－ＲＣＳ）和ＧＭＡ红细胞悬液（ＧＭＡ—ＲＣＳ），置４℃保存，于保存０．７、１４、２１、２８、３５、４２天取样测定ＡＴＰ、２，３—ＤＰＧ、红细胞酵解率、上清血红蛋白、平均红细胞体积等，结果示ＧＭＡ—ＲＣＳ在不同的保存时间阶段各项指标优于ＳＡＧＭ—ＲＣＳ在保存期末（４２天）ＧＭＡ－ＲＣＳ红细胞内ＡＴＰ含量为２．５５±０．４３±μｍｏｌ／ｇＨｂ，２，３—ＤＰＧ含量为２．２７±０．８０μｍｏｌ／ｇＨｂ，红细胞酵解率达８２％±１４％，上清血红蛋白３３３．６０±１８３．６５ｍｇ／Ｌ平均红细胞体积基本无变化。提示用ＧＭＡ保存红细胞的有效保存期可达４２天，保存效果良好。更多还原

【Abstract】 MA (Glucose, Mannital,Adenine)is an optimized additive solution developedfor suspension and preservation of red cell.It was compared to SAGM additive solu tion in the effect of red cell storage. Red cells were suspended in GMA and SAGMrespectively and stored for 42 days a, 4℃. Several measurement tests about the qualityof red cell suspension were performed during storage period.After 42 days,the maindata of GMA red cell suspension were the follows; ATP 2.55 ± 0.43μmol/gHb, 2,3 DPG 2.27± 0.80μmol/gHb, glucolysis rate 82+14%,supernatant Hb 333.60 ±183.65mg/1.The result indicateol that GMA additive、solution appeared an improved effectfor red cell preservation.更多还原