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核素介入治疗肝癌的初步报道
Preliminary report of radionuclide intervention therapy in liver cancer
【摘要】 用核素90Y-玻璃微球在超声穿刺引导下,对已失去手术指征的9例肝癌患者进行直接肝癌肿块内包埋介人治疗。其中4例为原发性肝癌,5例为转移性肝癌,取得了较好的疗效。在治疗后的两个月中,通过B超在形态学和病理切片与涂片在组织细胞学方面进行复查随访。结果表明,无论原发性与转移性的癌性肿块,B超提示肝癌肿块发生不同程度的密度改变,其中1例低密度区基本消失。病理提示肝癌细胞存在不同程度的坏死,有的呈坏死后残留空隙改变。此方法对肝癌破坏性大,疗效好.对周围器官损伤小,被治疗者痛苦小,为失去手术指征的肝癌患者提供有效的治疗手段。治疗后血常规、肝肾功能、出凝血时间均无明显变化。
【Abstract】 cases of liver cancer (4 primary and 5 metatic) using 90Y-glass traped microspere injected into the unresected liver masses guided by realtime liver echography were reported. Two months later B ultrasound indicated there was a density change of the tumor mass with various magnitude, among them low density area almost disappeared in one case. The gistologic studies showed some tumor cells becaxne nectotic and leaves a hollow space. No patients complained discomfort or pain during and after treatment. It is not harmful to surrounding tissues. therefore this method may be an effective therapy modality to treat the inoperable liver cancer without obvious side effects.
【Key words】 Radionuclide imaging; B ultrasound scan;  ̄90Y-glass microsphere; Intervention ultrasound;
- 【文献出处】 核技术 ,NUCLEAR TECHNIQUES , 编辑部邮箱 ,1995年11期
- 【分类号】R735.7
- 【被引频次】1
- 【下载频次】22