节点文献

慢性乙型肝炎干扰素治疗前后血清β2-微球蛋白的表达

The expression of the serum β2-MG after and before interferon-alpha in hepetitis B.

  • 推荐 CAJ下载
  • PDF下载
  • 不支持迅雷等下载工具,请取消加速工具后下载。

【作者】 孙绍武; 张月萍; 潘文君; 张艳红;

【Author】 Sun Shaowu. et al. Research Unit of Liver Disease,Lanzhou First People’s Hospital.Lanzhou 730050

【机构】 兰州市第一人民医院肝病研究室; 兰州市第一人民医院肝病研究室;

【摘要】 对慢性乙型肝炎30例治疗前后及治疗期间用RIA法测定血清中β2-微球蛋白(β2-MG)水平及HBV标志。结果表明,在α-干扰素治疗前或治疗后血清中β2-MG水平升高者疗效满意,相反则差。经统计学处理二者有明显差异(P<0.05)。因此认为,血清中β2-MG表达水平有助于干扰素疗效的判定,并可作为一个间接指标。

【Abstract】 Therapeutic effect and mechanism to interferon-alpha on 30 patients with hepatitis B virus inffection were studied.The level of serum β2-MG and HBV markers were measured after before and period of interferon-alpha therapy.The results show that highter level of serum β2-MG after or before of interferon-alpha therapy therapeutic effect were better than the lowers.The difference were statistically significant (P < 0.05).It’s suggest that the level of expression in serum β2-MG will be helpful to judge of therapeutic effect of interferon-alpha and may as a indirect indication.

【关键词】 乙型肝炎; 干扰素; β2-微球蛋白(β2-MG);
【Key words】 HBV; interferon-alpha; β2 MG;
  • 【文献出处】 甘肃医药 , 编辑部邮箱 ,1995年02期
  • 【分类号】R512.62
  • 【下载频次】21
节点文献中: