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老年脑血栓患者血浆中t-PA、PAI的变化

Change in t-PA, PAI in plasma of the Old Patients with Cerebral Thrombosis

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【作者】 王细福张昆南高幼奇赖 瑶谢旭芳屈新辉

【Author】 Wang Xlfu; ZhangKunlan; Gao Youqi; et al(Department of Neurology, Jiang Xi Provinecial People’s Hospital, Nanchang, 330006)

【机构】 江西省人民医院神经科

【摘要】 本文采用发色底物显色法对39例脑血栓患者血浆中组织型纤溶酶原激活物(t-PA)和纤溶酶原激活物抑制物(PAI)进行检测。结果t-PA活性下降,PAI活性升高,与健康对照组相比有显著差异性(P<0.01),表明脑血栓患者纤溶活性降低,是产生血栓的因素之一。本栓测结果提示,测定t-PA、PAI有助于脑血栓的诊断。

【Abstract】 We determinated the contents of tissue plasminogen activator(t-PA)and plasminogen activator inhibitor(PAI)in plasma of 39 cases with cerebral thromhosis. The results showed the activity of t-PA reduced and the activity of PAI increased. There was remarkable difference between patient’s group and control group(P<0. 01). It revealed that the activity of fibrinogem dissolution reducd, which is the one reason of cerebral thrombosis. The results illustrated that determination of t-PA and PAI are assistant to diagnose cerebral thrombosis.

  • 【文献出处】 临床实用神经疾病杂志 , 编辑部邮箱 ,1994年04期
  • 【分类号】R743.32
  • 【下载频次】20
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