【摘要】 目前螺旋霉素发酵生产中培养基氮源多用鱼粉或黄豆饼粉。黄豆饼粉的优点是原材料质量稳定，染菌率低，但发酵效价相对较低。以鱼粉作氮源发酵效价相对较高，但鱼粉质量不稳定。本研究对培养基配方进行改进，在黄豆饼粉配方中加入动物蛋白ＮＹ，提高了发酵水平。后采用正交设计对黄豆饼粉、ＮＹ、葡萄糖、淀粉四个因素作三水平试验，最终得到最佳培养基配方：黄豆饼粉２％，ＮＹｏ．５％，淀粉７．０％，发酵效价为原配方效价的１４０．９２％，证实了新配方的可靠性。更多还原

【Abstract】 A new composition of medium for Spiramycin fermen·tation was d eveloped. When animal protein NY instead of fish meal was used,the potency of Spiramycin was increased by 32.29%。 The medium composition for fermentation has been selected by means of orthogonal anaivsis method. The optimal ingredients of the medium consist of soybe an mill 2%, NY 0.5%,and starch 7.0%。 By using such new medium,the potency of Spiramycin was increased by 40.92%。更多还原