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大理州1044名儿童7种疫苗免疫水平现状监测

The Surveillance on the Present situation of Immune Levels of 1044 Children Vaccinated with Seven Kinds of Vaccines in Dali Prefecture

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【作者】 王家龙李洁胡汝源施吉昌杨武贤

【Author】 Wang jialong,et al.,Dali Prefecture Hygiene and Epidemic Prevention Station,Yunnan Province 671000

【机构】 云南大理白族自治州卫生防疫站

【摘要】 1991年分层随机抽取12个县(市)的4、8、12岁组儿童1044名,按卫生部《计划免疫技术管理规程》对7种疫苗的免疫现状进行了监测。结果:抗体阳性率、GMT分别为:麻疹87.16%±3.14%、5.83±0.41(<1:8者56.90%);百日咳78.13%±9.19%、218.10±23.39(≥1:320者41.62%);DAT 74.47%±11.04%、0.098±0.025;TAT 75.86%±11.09%、0.136±0.03;脊灰(ELISA):Ⅰ型89.99%、220.51,Ⅱ型83.38%、201.27,Ⅲ型86.09%、275.08,三个型79.48%、255.91(≥1:400者27.23%);乙脑(HI)67.47%±3.34%、39.44±1.48;OT试验阳性率24.73%。县市间、年龄组间差异显著(P<0.01)。4岁组调查接种率与免疫监测结果一致。麻疹抗体水平与发病呈完全负相关。基础免疫较好而加强免疫不够,甚至有免疫空白点、带。脊灰、麻疹、乙脑等的人群免疫屏障不够完善,有局部流行或爆发的可能。建议尽快进行5~14岁儿童的麻苗普种和5岁以下儿童的脊灰疫苗普服,加强村医培训,?

【Abstract】 total of 1044 children selected in age groups of 4, 8 and 12 years old from 12 coun- ties(cities )with stratified random sampling method were monitored on the present situa- tion of immune levels according to the prog- ramme on immunization in 1991.The results showed that the positive rates and the geome- tric mean titers of antibodies to measles were 87.16%±3.14%,5.83±0.41(56.90%,<1:8),respectively;to pertussis were 78.13%±9.19%218,10±23.39(41.62%,≥1: 320); to DATwere 74.47%±11.04%,0.098±0.025; to TAT were75.86%±11.09%,0.136±0.03;to poliomyelitis(ELISA )were type Ⅰ 89.99Ⅰ%, 220.51. type Ⅱ83.38%,201.27, type Ⅲ 86.09%,275.08,3 types79.48%,255.91 ( 27.23%,≥1:400); to JapaneseB encephalitis(HI)were 67.47%±3.34%,39.44±1.48.The conversion of OT was 24.73%.Itshowed signifioant difference among thesecounties and among 3 age groups(P<0.01).In 4-year age group,the vaccinated rate andtbe result of immune surveilance were thesame.The ant ibody level and the incide nceof measles showed negative correlation.

【关键词】 抗体水平监测免疫屏障
【Key words】 Antibody level SurveillanceImmunel evel
  • 【文献出处】 中华流行病学杂志 ,CHINESE JOURNAL OF EPIDEMIOLOGY , 编辑部邮箱 ,1994年03期
  • 【分类号】R392.7
  • 【被引频次】1
  • 【下载频次】34
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