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卵巢交界性上皮性肿瘤的治疗方式及预后

The treatment of borderline ovarian tumors andits prognosis

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【作者】 李自新秋肖凡

【Author】 .Li zi-xin;Qiu Xiao-fan.( People’sHospital, Beijing Medical University,100044.)

【机构】 北京医科大学附属人民医院妇产科

【摘要】 分析1965~1992年卵巢交界性上皮性肿瘤20例的临床资料及随访结果。其中浆液性9例,粘液性II例。临床I期15例,II期3例,III期2例。12例行全子宫及单侧或双侧附件切除,其中2例死于肿瘤复发。8例行单侧附件切除,无死于肿瘤复发者。14例进行术后化疗,现12例仍存活,占92.3%;死亡2例,1例为III期患者,另1例死于其他疾病。未化疗者6例,其中3例Ia期患者健在;死亡1例,为Ib期。结果提不:预后与手术方式关系不密切,而与分期有关;对具有高危因素,如外生乳头、肿瘤破裂、腹水等患者,以进行化疗为宜。

【Abstract】 wenty patients with ovarian borderline epithelialtumors were analysed.The tumor in 9 patients wereserous and in 11 patients mucinous in nature type.15cases were classified as of stage I,3 cases of stage IIand 2 cases of stage III, according to the FIGOstaging.All pathologic slides were re-reviewed to con-firm the diagnosis and no patients were lost tofollow-up. Total hysterectomy and unilateral or bilateralsalpingo-oophorectomy were done in 12 patients,among whom,2 died of tumor recurrenees.Unilateraladnexectomy was done in 8 patIents, and none died oftumor recurrence. Fourteen patients received postoperative chemotherapy 1~8 courses with PACregimen,12 patients were alive up to the present. Sixpatients did not receive chemotherapy and amongthese 3 with stage Ia were alive and 1 with stage Ibdied of tumor recurrenccs.The survival rate of stage 1was 92.3%. Our results indicated that the prognosis was close-ly related to clinical staging.We suggested that pa-tients of stage 1 who wish to preserve childbearingfunction may be treated with unilateral salpingo-oophorectomy,and chemotherapy should be given tothe patients with high risk factors、Because of the indo-lent nature of these tumors,long-term follow-up atleast 10 years is nccessary.

  • 【文献出处】 中华妇产科杂志 ,Chinese Journal of Obstetrics And Gynecology , 编辑部邮箱 ,1994年04期
  • 【分类号】R737.31
  • 【被引频次】7
  • 【下载频次】81
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