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桂附地黄丸浸膏对兔IgG加速型小鼠肾毒血清肾炎的影响
The Effects of Guifu Dihuang Pills Extract on Rabbit IgG Accelerated Mouse Nephritis Induced by Nephrotoxic Serum
【摘要】 桂附地黄丸浸膏能使兔IgG加速型肾毒血清肾炎小鼠血清白蛋白升高,尿蛋白、血清尿素氮、血清总胆固醇降低,并能改善肾组织病变,其0.3,1.2g/kg两剂量与环磷酰胺0.015g/kg作用相当。
【Abstract】 he effects of Guifu Dihuang Pills extract were observed in rabbit IgG accelerated mouse nephritis model in-duced by nephrotoxic serum. The results showed that this preparation could increase serum albumin,reduce urineprotein,serum urea nitrogen and total cholesterol in serum,and improve the histologicaUesions in kidneys. Theeffects of GuiJu Dihuang Pills extract in dosages of 0.3g/kg and 1. 2g/kg were similar to those of cyclophosphamide0.05g/kg.
【关键词】 桂附地黄丸浸膏;
兔IgG;
肾炎;
肾小球基底膜(GBM);
环磷酰胺;
【Key words】 Guifu Dihuang Pills extract; rabbit IgG; nephritis; glomerular basement membrane(GBM); cyclophosphamide;
【Key words】 Guifu Dihuang Pills extract; rabbit IgG; nephritis; glomerular basement membrane(GBM); cyclophosphamide;
- 【文献出处】 中国中药杂志 ,CHINA JOURNAL OF CHINESE MATERIA MEDICA , 编辑部邮箱 ,1994年05期
- 【分类号】R285.5
- 【被引频次】4
- 【下载频次】74