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微量垂直板状聚丙烯酰胺凝胶电泳在癌相关蛋白检测中的价值
The Role Microdose-Plate-Polyacryamide Gel-Electrophoresis in Determination of Cancer-associated Proteins
【摘要】 本文报道用微量垂直板状聚丙烯酰胺凝胶电泳法检测450例癌患者,338例良性病患者和117名健康对照的结果。三组人群的阳性率分别为45.56%,12.4%和6.84%,与文献报道用同样的方法、和评判标准所得结果(75.5%,7.6%及 3.6%)有所不同,并再探讨该方法在癌筛选中的应用价值。
【Abstract】 This paper reports the results of determining cancer-associated proteins in 450 patients with cancer,338 cases with benign disease and 117 normal specimens by mierodose-plate-polyacryamide gel-electrophoresis and the positive rate were 45.56%,12. 43% and 6. 84% respectively. According to standard set by Ren Hui-ming,the result was differ- ent from that of Ren Hui-ming’s despite the fact that the same technic and standard were used. The sensitivity in cases with carcinoma was not high enough to be used as a detecting method.
【关键词】 聚丙烯酰胺凝胶电泳;
癌相关蛋白;
肿瘤标志;
【Key words】 Polyacryamide gel-electrophoresis; Carcinoma; Cancer-associated protein; Tumor marker;
【Key words】 Polyacryamide gel-electrophoresis; Carcinoma; Cancer-associated protein; Tumor marker;
- 【文献出处】 中国肿瘤临床 ,Chinese Journal of Clinical Oncology , 编辑部邮箱 ,1993年11期
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