【摘要】 实验比较了甲状腺功能亢进(甲亢)、甲状腺功能减退(甲减)和对照组大鼠血浆中心钠素(ANF)、血管紧张素Ⅱ(ATⅡ)和醛固酮(ALD)的相关关系。结果表明甲亢大鼠血浆中ATⅡ和ALD明显高于对照组(P<0.05),而ANF升高的更为明显(P<0.01)。相反甲减大鼠血浆ALD明显低于对照组(P<0.05),而ATⅡ和ANF则降低的更为显著(P<0.01),结果提示在甲状腺功能异常的病理过程中,血浆ATⅡ和ALD首先发生变化,从而引起血浆ANE释放量发生变化来调节机体的相对平衡。更多还原

【Abstract】 The relation between aritrian natriuretic factor (ANF), angiotension Ⅱ(AT Ⅱ) and aldosterone (ALD) in plasma of rats with various thyroid functions (hyper-thyroidism, hypothyroidism and control group) were studied. The result showed that in hy-perthyroidic rat the concentration of AT Ⅱ(P<0.05), ALD and ANF (P<0.01) were higherthan that of the control group. On the contrary, in hypothyroidic rat the ALD plasma con-cent was lower (P<0.05), while AT Ⅱ and ANF were much lower (P<0.01) than thatof the control group. These results suggested that during the pathological progress of thethyriod disfunction AT Ⅱ and ALD concent in plasma changed at first, then ANF wasreleased to maintain the normal balance.更多还原