【摘要】 本文检测了40例急性白血病、35例良性血液病及58例正常人血清前清蛋白（PA）、α₁-抗胰蛋白酶（α₁-AT）、α₁-酸性糖蛋白（α₁-AG）、结合珠蛋白（HP）、转铁蛋白（TF）、唾液酸（SA）共六项指标,发现急性白血病组α₁-AT、α₁-AG、SA明显增高（P<0.01）;急性白血病缓解组α₁-AT、α₁-AG、SA明显降低（P<0.01）.分别对各组各项指标与相应SA作直线相关分析,结果表明急性白血病组PA与SA呈负相关（P<0.01）;α₁-AT及α₁-AG则分别与SA呈正相关（P<0.01）,提示疾病时SA增高确与某些急相蛋白成分改变有关更多还原

【Abstract】 Serum concentrations of prealbumin(PA), α1-antitrypsin (α1-AT), α1-acid glyc-oprotein(α1-AG), haptoglobin(HP), uransferrin(TF) and sialic acid(SA) were measured in 40 patients with leukemia and 35 patients with benign hematologic desea-scs. The results showed that compared with tnormal controls, serum α1-AG, α1-AT, SA were significantly higher and TF was significantly lower (P<0.01); during remission period of acute leukemia, serum α1-AG, αa1-AT, SA were decreased, but TF level remained lower. Serum α1-AG was also increased in benign hematologic deseases, but it was lower than that in patients with acute leukemia(not in remission). It was also shown that the raised concentration of sialic acid in leukemia correlated with some kinds of increased acute phase proteins更多还原