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重组组织型纤溶酶原激活剂治疗急性心肌梗塞

THE USE OF RECOMBINANT TISSUE-TYPE PLASMINOGEN ACTIVATOR IN THE TREATMENT OF ACUTE MYOCARDIAL INFARCTION: A CLINICAL ANALYSIS OF 15 PANTIENTS

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【作者】 陈国伟李兆文潘永良邓志豪杨柯李婺芳郭有方林月娥

【Author】 Chen Guowei(Departmenn of Internal Medicine, First Affiliated Hospital) Li Zhaowen Pan Yongliang Den Zhihao Yang KeLi Wufang Guo Youfang Lin Yue’e( Intensive Care Unit, Kiang Wu Hospital, Macau )

【机构】 中山医科大学附属第一医院心内科澳门镜湖医院加强监护病室澳门镜湖医院加强监护病室

【摘要】 应用重组组织型纤溶酶原激活剂(rt-PA)治疗15例急性心肌梗塞,对其临床效果进行分析,证实rt-PA具有缩小梗塞面积,改善心功能,提高患者生活质量和降低死亡率的作用,在使用过程中,本组病例未见到严重出血及其他严重副作用。作者对rt-PA的给药时机、应用指征及禁忌症作了探讨。

【Abstract】 This paper reports the use of recombinant tissue-type plasminogen activator (rt-PA) thine treatment of 15 pantients of acute myocardial infarction. The clinical effects of the rt-PA were analysed. The benefits of the rt-PA may included:(1) decrease the size of myocardial infarction; (2) improvement of left ventricular function; (3) improvement of live quality of pantients, and(4) reduction in mortality. No serious hemorrhage and other serious side effects were found during the treatment with rt-PA in our pantients. Administration time, indication and contraindication of the rt-PA were discussed.

  • 【文献出处】 中山医科大学学报 , 编辑部邮箱 ,1991年02期
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