【摘要】 以³H-TdR掺入法检测了甲状腺素在体外对正常小鼠脾淋巴细胞、S₁₈₀荷瘤鼠脾淋巴细胞及胸腺细胞转化的影响,并对ConA刺激相应细胞转化的影响进行了研究。结果表明,甲状腺素对正常小鼠脾淋巴细胞、荷瘤鼠脾淋巴细胞及胸腺细胞的转化作用与对照组比较均有差异（P<0.05,P<0.01）,甲状腺素可明显提高ConA刺激相应细胞转化。表明甲状腺素对机体细胞免疫有促进作用。更多还原

【Abstract】 ³H-TdR incorporation technique was employed to study the effect of thyroxine on transformation of spleen lymphocyte in normal and in S₁₈₀tumor-bearing mice as well as the effect on these cells that was pro-duced by ConA stimulation.The results indicated that there was a markedly difference of transformation effect between the thyroxine treated group in-clude normal spleen lymphocyte of mice as well as the spleen lymphocyteand thymocyte of tumor-bearing mice（P<0.01,P<0.05,P<0.01）.The result also shown that thyroxine can markedly increase the incorporation number of ³H-TdR of these cells stimulated by ConA（P<0.01,P<0.001,P<0.01）.Our study provide an evidance that thyroxine can enhance the cellulor immune effect and suggest an effect mechanism in the clinical applica-tion.更多还原