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载脂蛋白对某些中、老年心血管疾病的诊断价值
DIAGNOSTIC VALUE OF APOLIPROTEIN IN SOME CARDIOVASCULAR DISEASES OF MIDDLE AND OLD AGE
【摘要】 用单向免疫扩散法测定正常人96例和冠心病、高血压病、老年性主动脉瓣钙化及慢性胆囊炎患者共85例的血清载脂蛋白、TC、TG.HDL—C、LDL—C、VLDL—C。结果表明apo—AI的降低及apo—B值的升高不单是预测冠心病的指标,而且是预测动脉硬化的指标。apo—AI/apo—B比值的下降,与脂代谢紊乱有关或由其引起的疾病均可出现,因而血清载脂蛋白不能作为诊断冠心病的最好指标。
【Abstract】 Serum apoliprotein, TC, TG, HDL-C, LDL-C and VLDL-C were measured by single radio-mmunodiffusion in 96 normal subjects and 85 patients suffered from coronary heart disease CHD), hypertension, senile aortic calcification and chronic cholecystitis. It was shown that ecrease of apo-A1 and elevation of apo-B indicated not only as predictor ot CHD but also that f atherosclerosis as well. The reduction of the ratio between apo-A1 and apo-B would occur in ipid metabolic disorders and consequent diseases. So the determination of serum apo-liprotein ight not be the best diagnostic criterion of CHD.
- 【文献出处】 安徽医学 ,Anhui Medical Journal , 编辑部邮箱 ,1991年02期
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