【摘要】 应用放射免疫测定法,对20例胃肠癌患者进行了血清癌胚抗原(CEA)测定,并应用免疫组化法对其中16例癌组织中的CEA进行了检测.检测结果,血清CEA阳性6例,癌组织CEA阳性9例.低分化癌的血清CEA显著高于高分化癌(P<0.05).血清CEA与癌灶部位、癌组织CEA与分化程度及血清CEA均无关(P>0.05).提示血清CEA的含量与癌组织的分化程度有关,血清CEA与癌组织内的CEA无平行关系.作者并对其机制及检测CEA的意义进行讨论.更多还原

【Abstract】 The serum CEA levels were measured by radioimmunoassay in 20 patients with primary gastrointestinal carcinoma. 16 cases were stained for CEA in tissue sections by immunohistochemical technique. The results showed that there were 6 cases whose serum CEA levels were positive and 9 cases with positive tissue staining. Serum CEA levels were higher in poorly differentiated carcinoma than in highly differentiated type (P<0.05), but not related to the site of carcinoma, the degree of differentiation or the results of tissue CEA-staining (P>0.05). The possible mechanism and significance of CEA detection in gastrointestinal carcinomas are also discussed in this paper.更多还原