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树参叶抗心律失常作用的研究

Studies on Antiarrhythmic Effects of the Leaves of Dendropanax chevalieri (Vig.) Merr. et Chun.

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【作者】 黄敬耀; 刘春梅; 齐丕骝; 刘康民;

【Author】 Huang Jingyao, Liu Chunmei, Qi Piliu Liu Kangmin(Jiangxi College of Traditional Chinese Medicine, Nanchang)

【机构】 江西中医学院; 江西中医学院 南昌; 南昌; 南昌 八三级中药班毕业实习生;

【摘要】 树参叶水提物灌胃给药对乌头碱、CaCl2诱发的小鼠心律失常和BaCl2所致的大鼠心律失常均有明显的保护作用;静注给药能显著缩短肾上腺素诱发的麻醉兔心律失常的持续时间;还能明显推迟哇巴因性豚鼠离体心脏心律失常和心电消失的出现。

【Abstract】 Aqueous extract of the leaves of Dendropanax chevalieri (DC), administrated orally, showed prominent protective effect against arrhythmias induced by iv aconitine CaCl2(120mg/kg)in mice and BaCl2 (4mg/kg) in rats. In anesthetized rabbits, the duration of arrhythmia elicited by iv Adr 75μg/kg was markedly shortened by iv DC 0.4g/kg. It might also obviously delay the onset of arrhythmias and cardiac electricity disappearance evoked by ouabain perfusing consistently into isolated guinea-pig hearts.

【关键词】 树参; 抗心律失常;
【Key words】 Dendropanax chevalieri; antiarrhythmia;
  • 【文献出处】 中国中药杂志 ,China Journal of Chinese Materia Medica , 编辑部邮箱 ,1989年06期
  • 【被引频次】19
  • 【下载频次】143
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