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“健脑灵”对小鼠学习记忆的促进作用

Memory Facilitation Induced by Jian Nao Ling in Mice

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【摘要】 采用一次性被动回避条件反应——跳台法及避暗法行为实验和3种化学药物所致记忆障碍的模型,观察了健脑灵对小鼠学习记忆的影响。结果表明,健脑灵(800mg/kg)可改善东茛菪碱引起的记忆获得障碍;并对蛋白质合成抑制剂(氯霉素)造成的记忆巩固不良以及30%乙醇引起的记忆再现障碍均有拮抗作用。

【Abstract】 The effect of Jian Nao Ling (main component: lecithine) on memory in mice was studied by using One Trial Passive Avoidance Responses. The results indicate that Jian Nao Ling can improve the impairment of acquisition of memory produced by scopolamine, and disruption of consolidation of memory caused by chloramphenicol. Jian Nao Ling is capable of antagonizing the deficit of retrieval of memory induced by 30% alcohol.

【关键词】 氯霉素; 东莨菪碱; 学习; 记忆;
【Key words】 brain; learning and memory; phospholipids; drug combination;
  • 【文献出处】 延边医学院学报 ,Journal of Medical Science Yanbian University , 编辑部邮箱 ,1989年04期
  • 【被引频次】2
  • 【下载频次】26
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