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抗小麦赤霉病抗生素861-A的提取、纯化及理化性质
ISOLATION, PURIFICATION AND PHYSICO-CHEMICAL PROPERTIES OF ANTIBIOTIC 861-A USED FOR WHEAT SCAB CONTROL
【摘要】 <正> 小麦赤霉病是小麦的主要病害之一。在筛选防治小麦赤霉病的农用抗生素过程中,分离到链霉菌861菌株,定名为玫瑰皮黄链霉菌淡色变种(Streptomyces roseoalutaceus var,pallidus)。它的发酵液具有广谱的抗菌活性,经提取分离得到三个组份,其主要活性组分为抗生素861-A。经大面积作物防病药剂试验表明,对小麦赤霉病的防效达80—97%。本文报道其提取、分离及理化性质。
【Abstract】 Antibiotic 861 complex, isolated from Streptomyces roseoalutaceus var. pallidus by ion exchange chromatography, exhibits a broad antibacterial spectrum and a unique controlling efficiency to wheat scab, which is the major wheat disease in China. The complex was further purified by carbon column, acetone precipitation and CM-Sephadex G-25 ion exchange chromatography or high-performance liquid chromatography, and 861-A, the major effective component, was then obtained.Antibiotic 861-A is basic, hydroscopic white powder. It is very soluble in water and not soluble in normal organic solvents. A series of physico-chemical properties indicated that 861-A is a N-glycoside compound and identical with streptothricin F.
- 【文献出处】 微生物学报 ,Acta Microbiologica Sinica , 编辑部邮箱 ,1989年04期
- 【被引频次】15
- 【下载频次】74