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冬虫夏草免疫增强作用机理的研究

STUDIES ON EFFECTS OF CORDYCEP SINENSIS (BERK) SACC ON LYMPHOCYTE FUNCTIONS

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【作者】 匡彦德; 王美英; 钱琴芳; 谢家骏; 曹蓓莉; 关惠贞; 吴耀晴;

【Author】 Kuang Yande Wang Meiying Qian Qinfang Xie YiajunCao Beili Guan Huizhen Wu YaojingDepartment of Immunology, Shanghai Medical University,Shanghai Chinese Drug Research Institute

【机构】 上海医科大学基础医学部免疫学教研室; 上海中药研究所; 上海医科大学基础医学部免疫学教研室;

【摘要】 冬虫夏草水提取液对小鼠胸腺细胞、脾细胞以及脾细胞经除去thy-1+细胞后残存的细胞都有与剂量相关的致有丝分裂作用,说明虫草对T和B淋巴细胞的增殖有作用。虫草与脾细胞共育24小时的上清液中不能检出或仅能检出极低IL2活性,但虫草活化的脾细胞表达与ConA活化的脾细胞相近数量的IL2受体。

【Abstract】 The mitogenic effects of Gordyceps Sinensis (Berk) Sacc (CSS) on murine thymo-cytes, spleen cells and the residual splenocytes after treating with anti-thy-1 antibody and complement were observed. CSS had a dose related mitogenic effects on all of those cells. The results indicated that OSS had mitogenic effects on T and B lymphocytes. We couldn’t detect or only detected very low interleukin 2 (IL 2) activity in the supernatant of spleen Cell cultured with CSS for 24 hours, but CSS-activated splenocytes were able to absorb IL 2 activity from culture medium.

【基金】 国家然科学基金
  • 【文献出处】 上海免疫学杂志 , 编辑部邮箱 ,1989年01期
  • 【被引频次】77
  • 【下载频次】331
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