【摘要】 以广西间日疟原虫实验感染39名志愿者,32名感染成功。其中经短潜伏期(平均16.4d)发病者25例(78.1％);7例(21.9％)属长潜伏期,平均274.7±29.3d(238～314)。凡属短潜伏期初发者都经一长潜隐期后复发,复发率100％;大多数复发1～2次,少数复发3次。经长潜伏期发病的7例中,2例没有复发,余5例亦仅复发1次。实验证明,广西虽地处亚热带,当地间日疟原虫仍属典型温带型;但与滇南和河南间日疟原虫相比,仍有其生物学上的某些差异。更多还原

【Abstract】 39 healthy volunteers were experimentally inoculated with Plasmodium vivax from Guangxi by mosquito bite, and 32 of them were successfully infected. 25 of the infected volunteers (78.1%) had a short incubation period (mean: 16.4 days) prior to the onset of malaria attack, while seven individuals had long-term incubation period of 238 to 314 days (mean: 274.7±29.3 days). Relapses occurred in all cases with short-term incubation period after a long latency without exception; most of them had l to 2 relapses, some, 3 relapses. Among the seven cases with long incubation period, only one relapse occurred in five, and the remaining two had no relapse at all. It was shown that although Guangxi was situated in subtropical zone, Plasmodium vivax there was characteristie of the temperate zone type. A comparison of Plasmodium vivax from Guangxi with those from south Yunnan and Henan suggested that they differ in the composition of sporozoite subpopulations classified arbitrarily according to the duration of development of bradysporozoites in hepatic cells.更多还原