【摘要】 用青蒿醚片剂及青蒿酯钠盐粉针剂,总剂量为160～800mg,治疗各种疟疾现症病人772例,临床治愈率100％。杀虫速度两药均较青蒿素等6种抗疟药快。青蒿酯钠针剂肌肉注射或静脉推注抢救凶险型疟疾25例,疗效满意,但1个月内两药的复燃率仍高达46.6％(304/652)。更多还原

【Abstract】 As artemether and artesunate are both soluble in water, they are able to overcome the difficulty of preparation caused by the insolubility of artemisinine. Treatment of 772 cases of various forms of malaria at a total dose of 160-800mg yielded excellent effect with 100% recovery rate, the parasite clearance time being shorter than that of artemisininc and six other antimalarial drugs. In particular, when treating 25 severe cases of malaria, sodium artesunate injection led to satisfactory result, either intramuscularly or intravenously. It is the most effective new antimalarial drug. There were no side-effects, and no significant influences on the function of heart, liver, kidney and other important organs. However, the recrudescence rate of 46.6%(304/652) was relatively high.更多还原