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胸膜斑的病理研究

Pathological Study of Pleural Plaques Caused by Asbestos Exposure

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【摘要】 本文集中了国内50例石棉作业工人尸检资料,其中有胸膜斑形成者30例。生前接触温石棉,平均工龄17.3年。除进行病理形态观察外,将胸膜斑按面积大小分成3度。石棉矿工胸膜斑的程度低于石棉制品工人。肺内石棉小体和裸纤维的数量虽与肺纤维化分期相一致,但与胸膜斑的分度未见相关关系。对35根石棉纤维做SEM—EDAx检查,除其中1根是温石棉外,34根均是闪石类石棉。9例消化的胸膜斑样品内只有1例查出少量闪石类石棉。胸膜斑是石棉所致的一种独特病变,是接触石棉的指征,诊断石棉肺时应对其意义加以考虑。

【Abstract】 Data from 50 autopsies of asbestos workers with life time exposure to chrysotile were collected and studied.Among them 30 were found to have pleural plaques.The sizes of the plaques were found to be larger and more severe in asbestos factory workers than those of asbestos miners,though total asbestos bodies and number of nude fibres failed to show statistical significance in relation to the size of plaques.35 asbestos fibres were examined by scanning electron microscope equipped with a Kevex Energy dispersive X-ray spectrometer,and 34 of these were fourd to belong to amphibole while only one to chrysotile.Small amount of amphiboles were found inone of the nine digested plaque tissues.It is suggested that pleural plaque andpulmonary fibrosis should be consideredas specific lessons caused by asbestosfibres,and the plaque is an indicationof exposure to asbestos.Therefore,the consideration should be taken whendiagnosing asbestosis.

【关键词】 石棉; 温石棉; 闪石类石棉; 病理; 胸膜斑; 扫描电镜。;
  • 【文献出处】 中华劳动卫生职业病杂志 ,Chinese Journal of Industrial Hygiene and Occupational Diseases , 编辑部邮箱 ,1988年01期
  • 【被引频次】9
  • 【下载频次】33
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